Sublingual Delivery of Frovatriptan: An Indication of Potential Alternative Route

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Sublingual Delivery of Frovatriptan: An Indication of Potential Alternative Route

Frovatriptan, a 5-HT1B and 5-HT1D receptor agonist, is used for the treatment of acute migraine attack. This molecule is classified into second line therapy because of its slow onset of action (peak response obtained after 4 hours of administration) and low bioavailability (25%). Moreover, its therapy is the most costly among all triptans. Attempt has been made in present work to suggest a way ...

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ژورنال

عنوان ژورنال: International Scholarly Research Notices

سال: 2014

ISSN: 2356-7872

DOI: 10.1155/2014/675868